Tahun Terbit

2004

Edisi

3

ISBN/ISSN

979-3249-54-4

Deskripsi Fisik

xvi,224p;ill ;20,5cm

No. Panggil

155.4 KHA a

The DNA damage response helps to maintain genome integrity, suppress tumorigenesis, and mediate the effects of radiotherapy and chemotherapy. Our previous studies have shown that Smad1 is upregulated and activated by Atm in DNA damage response, which can further bind to p53 and promote p53 stabilization. Herewe report another aspect of the interplay between p53 and Smad1. Comparison of recta…