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Cari koleksi dengan cepat sesuai kebutuhan Anda.X chromosome inactivation is a mechanism that modulates the expression of X-linked genes in eutherian females (XX). Ohno proposed that to achieve a proper balance between X-linked and autosomal genes, those on the active X should also undergo a 2-fold upregulation. Although some support for Ohno’s hypothesis has been provided through the years, recent genomic studies testing this hypothesis…