Severe combined immunodeficiency (SCID) has many phenotypes, including those which result in the formation of T cells but render them incapable of an optimal level of proliferation following stimulation by an antigen. Phytohaemagglutinin (PHA) is a mitogen commonly used to assess T-cell proliferation, although anti-CD2/CD3/CD28-coated beads may provide a more physiological trigger. Some patient…

Data from the School Success Profile generated by 19,228 middle and high school students were organized into three broad categories of risk and protective factors—control, support, and challenge—to examine the relative and combined power of aggregate scale scores in each category so as to predict academic success. It was hypothesized that higher control and higher support scores might predi…

Tahun Terbit

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Tahun Terbit

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School social workers can serve as valuable supporters of lesbian, gay, bisexual, and transgender (LGBT) youths in the public school system by providing services aimed to improve school climates for all students. This article describes a qualitative study that examined gay and bisexual adolescent experiences with peer support using a phenomenological inquiry approach. Five themes related to pee…

Reductions in cardiac infarct size can be achieved in ischaemic preconditioning, a procedure which subjects the heart to intermittent, non-lethal cycles of ischaemia and reperfusion. Similar cardioprotection can be induced upon preconditioning distal tissues such as the upper limb, and this procedure is called remote ischaemic preconditioning. Nano-sized, cell-derived vesicles known as exosomes…

There are few evaluations of peer-facilitated teenage dating violence prevention programs in the literature. To begin to address this gap, this project assessed the effectiveness of a schoolbased, peer-facilitated healthy relationships program among academically at-risk students. Two hundred and ninety-one ninth graders of mixed race and gender participated in a fivesession healthy relationship…

Many school-age children in the United States with social, emotional, and behavioral problems do not receive mental health services. These problems negatively affect their social and behavioral functioning and academic achievement. This is particularly a problem for Latino youths, who represent the largest ethnic minority group in the United States and the largest group with unmet need for ment…

With an ageing population, the incidence of Parkinson’s disease is increasing. The disease has an overwhelming impact on those it affects and has a limited repertoire of drug therapies available, each with problematic side effects. Stem cell therapy is an exciting prospect in the treatment of several neurodegenerative conditions. This article takes an in depth look at the great potential of c…

The release of extracellular vesicles (EVs), including exosomes and microvesicles, is a phenomenon shared by many cell types as a means of communicating with other cells and also potentially removing cell contents. The cargo of EVs includes the proteins, lipids, nucleic acids, and membrane receptors of the cells from which they originate. EVs released into the extracellular space can enter body…