Captain Smith’s ‘‘Ivie’’ was well known to his Powhatan Indian neighbors. For centuries, they and other Native Americans had used it for medicine. Navajos made arrow poison from this native plant, and California’s Miwoks made theWestern version, it-tum in their language, into black dye for baskets (Balls, 1962). They were very aware of its harmful character—in Mexico, it was calle…