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Cari koleksi dengan cepat sesuai kebutuhan Anda.Tumor cells secrete not only a variety of soluble factors, but also extracellular vesicles that are known to support the establishment of a favorable tumor niche by influencing the surrounding stromacells. Hereweshowthat tumor-derived microvesicles (T-MV) also directly influence the tumorcells byenhancing their invasion in a both autologousand heterologous manner. Neither the respective vesic…
Pten controls a signaling axis that is implicated to regulate cell proliferation, growth, survival, migration, and metabolism. The molecular mechanisms underlying the specificity of Pten responses to such diverse cellular functions are currently poorly understood. Herewe report the control of Pten activity and signaling specificity during the cell cycle by Ndfip1 regulation of Pten spatial dist…
We uncover a natural relationship between the Northcott property for sets of algebraic numbers and the Julia Robinson number associated to sets of algebraic integers. This implies, in particular, that any subring of a ring of totally real integers having the Northcott property has undecidable first-order theory. Combining this theorem with previous results by the second author, we prove that th…