Tahun Terbit

1994

Edisi

Ed. 2

ISBN/ISSN

0-8039-4653-8

Deskripsi Fisik

xiv, 338 p. : ill. , 28, 5 cm

No. Panggil

001.42 MIL q

Cynomolgus macaques (Macaca fascicularis) were introduced to the island of Mauritius by humans around the 16th century. The unique demographic history of the Mauritian cynomolgus macaques provides the opportunity to not only examine the genetic background of well-established non human primates for biomedical research but also understand the effect of an extreme population bottle neck on the pat…

Complex eukaryotic genomes are riddled with repeated sequences whose derivation does not coincide with phylogenetic history and thus is often unknown. Among such sequences, the capacity for transcriptional activity coupled with the adaptive use of reverse transcription can lead to adiverse group of genomic elements across tax a, other wise known as selfish elements or mobile elements. Sho…

Sequence capture and restrictions it eassociated DNA sequencing (RADseq) are popular methods for obtaining large numbers of loci for phylogenetic analysis. These methods are typically used to collect data at different evolutionary timescales; sequence capture is primarily used for obtaining conserved loci, whereas RADseq is designed for discovering single nucleotide polymorphisms (SNPs) suitabl…

How cells divide and differentiate is a fundamental question in organism al development; however, the discovery of differentiation processes invarious cell types is laborious and sometimes impossible. Phylogenetic analysisis typically used to reconstruct evolutionary processes based on inherent characters. It could also be used to reconstruct developmental processes based on the developmental c…

Epigenetic control of gene expression has important implications for the regulation of developmental processes, for mediating homeostasis and responses to the external environment, and for transgenerational inheritance of gene expression patterns. Genes that mediate epigenetic control have been well-characterized in Drosophila melanogaster, and we have identified and analyz edan orthologo…

The pronouncements of the ENCODE Project Consortium regarding “junkDNA” exposed the need for a nevolutionary classification of genomic elements according to their selected-effect function. In the classifications cheme presented here, we divide the genome into “functional DNA,” that is,DNA sequences that have a selected-effect function, and “rubbish DNA,” that is, sequen…

Fungi that have the enzymes cyanase and carbonican hydrase show a limited capacity to detoxify cyanate, a fungicide employed by both plants and humans. Here, we describe a novel two-gene cluster that comprises duplicated cyanase and carbonic anhydrase copies, which we name the CCA genecluster, trace it sevolution across As comycetes, and examine the evolutionary dynamics of its spread among lin…

This work is aimed to resolve the complex molecular evolution of cytochrome bd ubiquinol oxidase, a nearly ubiquitous bacterial enzyme that is involved in redox balance and bioenergetics. Previous studies have created an unclear picture of bd oxidases phylogenesis without considering the existence of diverse types of bd oxidases. Integrated approaches of genomic and protein analysis focused on …

Models of protein evolution are used to describe evolutionary processes, for phylogeneticanalyses and homology detection. Widely used general models of protein evolution are biased toward globular domains and lack resolution to describe evolutionary processes for other protein types. As three-dimensional structure is a major constraint to protein evolution, specific models have been propo…